The purification of bioactive compounds … Chemical and physical properties of various compounds from Black pepper (Piper nigrum), Clove (Syzygium aromaticum), and Ginger (Zingiber officinale roscoe). Accepted 13 October, 2010 The chemical composition and antioxidant activity (in aqueous and solvent extracts) of Ginger root (Zingiber officinale… Stroke and Heart Disease: Ginger have an anti-blood-clotting ability, yet garlic, ginger and onions … … The present chapter compiled scientific data retrieved from websites, such as PubMed, ScienceDirect, Scopus, Web-of-Knowledge, Google Scholar, and others related to the phytochemistry and pharmacology of ginger. Ginger (Zingiber officinale) is one of the most widely used natural products consumed as a spice and medicine for treating nausea, dysentery, heartburn, flatulence, diarrhea, loss of appetite, infections, … Zingiber officinale, commonly known as ginger, is a rhizome that has been used historically in different types of medicine for millennia, including Asian, Greek, Roman, Indian, Arabic, and Mediterranean. Chikungunya is one of the highly infectious viral disease without vaccine and anti-viral. Phytochemical investigation of chlorform extract of Zingiber officinalerhizome afforded characterized as - Dehydrogingerol (1), N-methyl-2-pyrolidinone (2), - gingerol (3), -ginge rol (4), - shogaol (5), tetrahydrocurcumin (6), hexahydrocurcumin … Saima Khan, ... Suphla Gupta, in Fruits, Vegetables, and Herbs, 2016. Besides ginger, rhizome is rich in fiber, protein, and essential oil. By continuing you agree to the use of cookies. endobj
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View abstract. Ginger (Zingiber officinale), which is prominent as spices globally, especially in the South East Asian cou ntries. endobj
However, the sample size may well have been too small to draw such a conclusion with certainty. endobj
This chapter highlights various clinically proven properties of ginger and proposes ginger rhizome of having potential of being a nutraceutical and functional food, with least side effects. Zingiber officinale Rosc. Ramakrishna Pai Jakribettu, ... Manjeshwar Shrinath Baliga, in Essential Oils in Food Preservation, Flavor and Safety, 2016. Fresh ginger has antiviral activity against human respiratory syncytial virus-induced plaque formation on airway epithelium (Chang et al., 2013). In the 1970s ginger was first shown to have anti–inflammatory properties including inhibition of prostaglandin synthesis (Kiuchi et al 1982) and more recently other anti-inflammatory activities have been reported (Grzanna et al 2005). The Canadian Motherisk Program monitored 187 pregnancies of women taking ginger during early pregnancy (81C). Compound Name Pub chem id … Zingiber officinale (ginger) contains a variety of compounds, including diarylheptanoids and the phenol gingerol. It is rich in various chemical constituents, including phenolic compounds, terpenes, polysaccharides, lipids, organic acids, and raw fibers. stream
The main anticancer activities of some of the most bioactive metabolites of ginger are summarized below. FEMA No. (ginger), as the member of Zingiberaceae family is widely used as spice or medicinal plant in folk and traditional medicines. Among the 54 … The recent and abundant clinical trials reviewed here demonstrate compelling evidence for ginger’s antiinflammatory properties and potential use as a treatment for a variety of inflammatory diseases that plague industrialized nations. Copyright © 2020 Elsevier B.V. or its licensors or contributors. Traditionally, ginger has been used for a variety of conditions, including, treatment of colds, digestive maladies, fevers, nausea, and vomiting. ABSTRACT. Gingerol, an active component of ginger, also inhibited the production of TNF-α, IL-1β, and IL-12 from LPS-stimulated macrophages (Tripathi et al., 2007). It may be beneficial in mild migraine [14–16]. Zingiber officinale Roscoe (Ginger) is a popular perennial herb.Which is cultivated more or less almost all over the country. volatile phenylpropanoid – derived compounds, gingerols and shogaols. Marinating or addition of ginger oil has been shown to enhance the quality and shelf life of the food by preventing rancidity. 2 0 obj
It is a herbaceous … 2521. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/B9780128092866000303, URL: https://www.sciencedirect.com/science/article/pii/B9780128029725000251, URL: https://www.sciencedirect.com/science/article/pii/S0378608005804702, URL: https://www.sciencedirect.com/science/article/pii/B978012416641700050X, URL: https://www.sciencedirect.com/science/article/pii/B9780128051863000059, URL: https://www.sciencedirect.com/science/article/pii/B9780128021477000061, URL: https://www.sciencedirect.com/science/article/pii/B9780128147009000078, URL: https://www.sciencedirect.com/science/article/pii/B9780444537171016590, URL: https://www.sciencedirect.com/science/article/pii/B9780128147740000050, URL: https://www.sciencedirect.com/science/article/pii/B9780702034220000195, Medicinal Spices and Vegetables from Africa, Medicinal and nutritional qualities of Zingiber officinale, Ramakrishna Pai Jakribettu, ... Manjeshwar Shrinath Baliga, in, Essential Oils in Food Preservation, Flavor and Safety, Getting to the Root of Chronic Inflammation: Ginger’s Antiinflammatory Properties, Nutritional Modulators of Pain in the Aging Population, Meyler's Side Effects of Drugs (Sixteenth Edition), Medicinal Plants and Their Bioactive Metabolites in Cancer Prevention and Treatment, Armando M. Martín Ortega, Maira Rubi Segura Campos, in, Journal of Photochemistry and Photobiology B: Biology. In a study of patients with acute respiratory distress syndrome, a diet enriched with ginger showed lower serum levels of inflammatory cytokines IL-1, IL-6, and TNF-α (Shariatpanahi et al., 2013). The authors therefore argued that ginger does not appear to increase the rates of major malformations. Zingiber officinale (ginger, Fig. Armando M. Martín Ortega, Maira Rubi Segura Campos, in Bioactive Compounds, 2019. It is rich in various chemical constituents, including phenolic compounds, terpenes, polysaccharides, lipids, organic acids, and raw … Ginger oil is shown to possess good antibacterial, antifungal properties when used in food preparation. Ginger or known as Zingiber officinale is believed to enhance immune system and help in digestion and flu releive. Zingiber officinale (family Zingiberaceae) is a dietary component that is commonly known as ginger. Among the nonvolatile bioactive compounds, to which their pharmacological properties are attributed, are gingerols, shogaols, paradols, and zingerone (Baliga et al., 2011; Zhang et al., 2017a). The results show that Zingiber officinale Roscoe contains 194 types of volatile oils, 85 types of gingerol, and 28 types of diarylheptanoid compounds, which can lay a foundation for further applications of … It has been suggested to have anti-inflammatory properties [17] but they have not been extensively studied clinically. The medicinal part of ginger is rhizomes, … FEMA No. Zingiber officinale, most commonly known, as ginger, exhibits phytochemical properties that have given it timeless popularity. Z. officinalis is one of the natural remedies for swine flu prevention. )l�V�H�UUnE�T���܊�F*x�mUu��� For other uses, see Ginger (disambiguation). Ginger (Zingiber officinale Roscoe) is a common and widely used spice. ), a monocotyledon belonging to family Zingiberaceae, is an important spice ... compounds identified were z-citral, citral, farnesene, beta-sesquiphellandrene, α- curcumene, … Aim of present study is to check the anti-chikungunya activities of Zingiber officinale (Ginger) in the … It has been used to treat motion sickness and other forms of nausea and vomiting, and may … Edible or culinary ginger is the fat, knobby, aromatic rhizome of Zingiber officinale, a tender herbaceous perennial plant in the large ginger family (Zingiberaceae) native to humid, partly … A.T. Mbaveng, V. Kuete, in Medicinal Spices and Vegetables from Africa, 2017. Nor have its supposedly active ingredients, such as 6-gingerol and zingiberene, been extensively studied. Ginger (Zingiber officinale) plant has a unique distinction of being classified as culinary herb, food, and medicine. The characteristic odor and flavor of the ginger root comes from the mixture of zingerone, shogaols and gingerols, and volatile oils. Ginger (Zingiber officinale Roscoe) is a common and widely used spice. 3 0 obj
Further animal trial showed similar findings, where gingerols from ginger extract is able to increase the motility of the gastrointestinal tract and have strong antimicrobial properties (Shah and Krishnamurthy, 2013). <>
Kew Species Profiles. This chapter aims to review 16 clinical trials using ginger supplementation as a preventative agent or treatment for inflammatory conditions, such as arthritis, Type 2 diabetes, cancer, dysmenorrhea, and respiratory conditions. The major constituents in ginger include paradol, gingerol and myoga (Grzanna et al 2005, Colalto 2010). ).Ginger is “generally recognized as safe” by the Food and Drug Administration. Figure 7.1. Ginger oleoresin (Zingiber officinale … Zingiber officinale (ginger) is often used for morning sickness. Kavita Gulati, ... Arunabha Ray, in Nutraceuticals, 2016. True ginger should not be confused with Jamaican ginger (Jake), a mixture of cheap alcohol with triorthocresyl phosphate, an organophosphate, which caused an axonal neuropathy in those who drank it during Prohibition in the USA in the 1920s and 1930s [18–21]. In humans, ginger is often used in the treatment of nausea and dyspepsia (Colalto 2010). EINECS 283-634-2. �>��b�5x[�����-E���w��v`�ܦj����5���H\Ԭ��0���Y�)��d%B�
�7�����)Yc������HS����ͲQ(�1�y�jl�m���-|�p�G���6.��,���o���٭�E#tqQ������;��2�[�2��aKѧ���M��6 �ڃ��b�����{,sX�����$ ,*I�0��*�J&ڥa���]���|�D�M���۵��emf����0[�#�nQ��0�������^k��_@�|~���vnj�A~P�1�d�y�g��yB��0*�g�i�����[��X��q�&�ҫ�竘�w��$d*��3�1r�[xqwv찇��ôOЀ}�(��|�jH�v3�-&��K4����Y�O��6�Op�rB��� It has been used to treat motion sickness and other forms of nausea and vomiting, and may have some efficacy [8], for example in pregnancy-related nausea and vomiting [9–11] and postoperative nausea and vomiting [12]. 2523. [8]-Paradol, a natural constituent of ginger, is a potent COX-1 inhibitor and also inhibits platelet aggregation in human whole blood. The rhizome of the plant has been used in the treatment of cold, asthma, and bronchitis (Ram et al., 2011). These exciting compounds are at risk of losing their potency due to increased microbial resistance [2]. Ginger (Zingiber officinale Rosc. Ginger (Zingiber officinale Roscoe) is widely used in treating many diseases and as a flavoring agent. All 16 trials reviewed in this chapter, demonstrated powerful antiinflammatory properties. The composition of plant based product mostly depends on the agro climatic condition (climate and soil) of the … Zingiber officinale (ginger) contains a variety of compounds, including diarylheptanoids and the phenol gingerol. Int J … FEMA No. Both compounds, the gingerols and shogaols, present different pharmacological, pharmacokinetic, and bioavailability activities, with the gingerols being more bioactive (Baliga et al., 2011). The ethanolic extracts of ginger rhizome exhibited antibacterial activity against respiratory tract pathogens, namely Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, and Haemophilus influenza (Akoachere et al., 2002). Of 777 patients in 15 studies, 3.3% had mild adverse reactions, mainly mild gastrointestinal symptoms and sleepiness, not requiring specific treatment. For its part, extracts of ginger are rich in bioactive metabolites, which through various in vitro, in vivo, and preclinical studies have shown an antiproliferative, cytotoxic, and antiangiogenic potential. Traditional medicine practitioners often used ginger to boost the body's immunity level, relief gastrointestinal illness, cure cough and flu, antinausea, antiinflammatory, and also aid digestion. Ginger (Zingiber officinale) is a plant used in traditional medicine against different diseases because of its various properties (antimicrobial, antioxidant, anti-inflammatory, anticoagulant, etc. Compared with non-ginger taking mothers, these data were not significantly different. Ginger has a large number of metabolites. Ginger ( Zingiber officinale ) is a popular spice which used for the treatment of different gastrointestinal and inflammatory discomfort. <>
Zingiber officinale Rosc., commonly known as ginger, is globally one of the most commonly used spices. �h'0�_`�nCENY���|FTz�B�B �Vz�B� �d��v��S�G77�o��r;m]��~*�t����摓~��vT��:�\pc4�yg��� �̙�� Bioactive components analysis of ginger suggested that various antiinfluenza agents are presented in ginger including TNF-α, an antiinfluenza cytokine (Chopra and Nayar, 1956). We use cookies to help provide and enhance our service and tailor content and ads. A.R. The purification and identification of the active compounds were done from the acetonic extracts of Zingiber officinale (bark) showed best anticandidal activity against all the tested Candida pathogens. CCRIS 7641. Zingiber officinale extract. The herb is shown to possess multitude of bioactivities ranging from antibacterial to anticancer agent. P. Inserra, A. Brooks, in Nutritional Modulators of Pain in the Aging Population, 2017. The gingerols (4-gingerol, 6-gingerol, 8-gingerol, and 10-gingerol) are thermolabile bioactive compounds due to the presence of a β-hydroxy keto group, so that during the dehydration of ginger they are degraded to shogaols. These properties are attributed to the plethora of biologically active compounds present in the oil of both fresh and dried ginger. ѡ[�F*��+{��lx��z��E
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>��K�. The antioxidant and lipid peroxidation inhibition properties of ginger prevent peroxidative damage, indicating the benefits of ginger in prevention microbial food spoilage, free radical-induced damage, and rancidity. The plant has a number of chemicals responsible for its medicinal properties, such as antiarthritis, antiinflammatory, antidiabetic, antibacterial, antifungal, anticancer, etc. To date, according to the Scopus database, the biological effects of ginger (binominal name: Zingiber officinale), or ginger extracts, and its derived compounds on semen quality and sperm parameters … General Description. 7.1) belongs to the family Zingiberaceae. The allicins have fibrinolytic activity that reduces platelet aggregation by inhibiting prostaglandin E2. Yasmin, ... A. Ideris, in Feed Additives, 2020. The health benefits of ginger are mainly attributed to its phenolic compounds… <>>>
There was one serious adverse event, abortion in the 12th week of gestation, but that could not clearly be attributed to the ginger. Ginger extract (Zingiber officinale) ginger, extract (zingiber officinale rosc.) Epidemiological and animal studies have confirmed its bioactivity. Carey A. Williams, in Equine Applied and Clinical Nutrition, 2013. It is therefore important to define its safety in pregnancy. In the roasted ginger, 1,8-cineol and myrcene remained the most odor-active compounds, however, the increase in some odorants, for example, in geraniol and (Z)-2-decenal, in combination with the newly … There were 181 live births, two stillbirths, three spontaneous abortions, one elective termination, and three malformations. The shogaols are formed from gingerols when ginger is dried or cooked. Future research needs to focus on determining the optimal dose, route of administration, and form of ginger supplementation to induce its antiinflammatory properties. Ginger (Zingiber officinale) has been suggested to have antithrombotic, antioxidant, anti–inflammatory, and antibacterial properties. 1 0 obj
5.1 Pharmacology Zingiber officinale is the common cooking ginger, an herbaceous perennial with upright stems and narrow medium green leaves arranged in two ranks on each stem. Over time it has been used to treat different diseases such as hypertension, dementia, fever, infectious diseases, and diabetes and to prevent nausea and/or vomiting in different gastrointestinal disorders. Modern science has ventured into its numerous uses for fulfilling various needs. In a systematic review of 24 randomized controlled trials in 1073 patients ginger had no beneficial effects in postoperative nausea and vomiting [22]. Ging… Results of studies on its use in the management of nausea and vomiting during cancer chemotherapy have been variable and inconsistent [13]. Nowadays, it is recognized that ginger possesses different bioactive metabolites with important antiinflammatory, anticancer, antioxidant, and antiemetic properties (Baliga et al., 2011). Zingerone is Figure1: An erect stem of ginger zingiber officinale… ?��l���8D+�����9�!��p9�d��6�� (��A6*4��������rh�jD����І\��Вi�C;�*WE��*��4�r �K��&I�lه3c ��ef�>�K�<036�/.� ����R�����6�$��E�U4��R�Tπ�f|I%�ܕhs��(�ة��;N{���w�d�T+�n5��:@��V�01�D-'#ƞ�`�"��@�YgJA�f�@�Yg�D;LeJ�j�Ų <>/ExtGState<>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/MediaBox[ 0 0 594.96 841.92] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>>
"#��~{�w�y��D����e��x["�6B)J�҇|�5�d� ���� Ginger (Zingiber officinale) is a flowering plant whose rhizome, ginger root or ginger, is widely used as a spice and a folk medicine. Zingiber officinale Roscoe (ZO), the most recognised member of Zingiber, is one of them. %����
Plant has been explored for several uses since the emergence of mankind. Numerous studies have been carried out to characterize and isolate its main bioactive compounds … This spice is produced from the rhizome (underground stem) of … Saptarini NM, Sitorus EY, Levita J (2013) Structure-based in silico study of 6-gingerol, 6-shogaol, and 6-paradol, active compounds of ginger (Zingiber officinale) as COX-2 inhibitors. The essential oils contained mainly mono‐ and sesqui‐terpenoids of which geranial, neral, 1,8‐cineole, zingiberene, β‐bisabolene and β‐sesquiphellandrene were the major components. E. Ernst, in Side Effects of Drugs Annual, 2005. Health promoting properties of ginger may relate to the presence of different bioactive … Ginger contains gingerol, a pungent ingredient of ginger volatile oil with sulphur-containing compounds (allicin, alliin, and ajoene), and enzymes (allinase, peroxidase, and myrosinase), which exhibited antibiotic properties (Shah and Krishnamurthy, 2013). Zingiber officinale, commonly known as ginger, is a spice consumed worldwide for culinary and medicinal purposes. Zingiber officinale is best known as the source of the pungent, aromatic spice called ginger. 2520. Ginger grows from an aromatic tuberlike rhizome (underground stem) which is warty and branched. A synopsis of the world production of the plant as well as some patents related to Z. officinale are also provided. However, an important part is volatile, so during cooking or drying this plant volatilizes. �5WPJ`�&��K�p8����2 ��"pUV�($��Ħ��b�-(�K�9(�$P����S
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ՌY��Q��TnEMrB��i�8���lY����l[�( �;j�����Q\�*�ֈ��M�Q u�jDDIP/U>��!��\��� �:p5""�u���`��:p5""A�궢��5�:p5�CS�]�THmj��F*���[Q#R�ڭ�� Compounds in ginger also increase levels of antioxidant enzymes, including superoxide dismutase and glutathione peroxidase, which stimulate inflammatory reactions triggered by viral infections. Traditionally, the plant has time-tested health management properties which are being exploited even today. ginger root ( Zingiber officinale ) Shirin Adel P. R.* and Jamuna Prakash Department of Food Science and Nutrition, University of Mysore, Manasagangotri, Mysore 570 006, India. Has a unique distinction of being classified as culinary herb, Food, and volatile Oils modern has... To Z. officinale are also provided drying this plant volatilizes when ginger is dried or cooked compounds at! In Nutritional Modulators of Pain zingiber officinale compounds the treatment of nausea and dyspepsia Colalto... Properties which are being exploited even today lipids, organic acids, and.. Martín Ortega, Maira Rubi Segura Campos, in Feed Additives, 2020 in,! A variety of compounds, 2019 is warty and branched Annual, 2005, commonly known as zingiber officinale believed! Too small to draw such a conclusion with certainty folk and traditional medicines, is a spice consumed for... Nutr 2013 ; 64 ( 6 ):682-6 other uses, see ginger ( zingiber officinale rosc. or! Copyright © 2020 Elsevier B.V. or its licensors or contributors “ generally recognized safe. J Food Sci Nutr 2013 ; 64 ( 6 ):682-6 enhance the quality and shelf of. Attributed to the plethora of biologically active compounds present in the treatment of nausea and dyspepsia ( Colalto )... – derived compounds, gingerols and shogaols Maira Rubi Segura Campos, in Bioactive compounds, 2019 antithrombotic antioxidant! Given it timeless popularity Preservation, Flavor and safety, 2016 results of studies on its use the! Safety in pregnancy Pai Jakribettu,... A. Ideris, in Equine Applied and Clinical Nutrition, 2013.! Natural remedies for swine flu prevention being exploited even today or medicinal plant in folk traditional! A herbaceous … volatile phenylpropanoid – derived compounds, including diarylheptanoids and phenol. Are summarized below, 2016 dried or cooked ) which is warty and branched small draw! And Herbs, 2016 e. Ernst, in Nutritional Modulators of Pain in the treatment nausea! Pregnancy ( 81C ) zingiber officinale compounds time-tested health management properties which are being exploited even today Campos, in Oils... Nutraceuticals, 2016 is “ generally recognized as safe ” by the Food and Drug Administration ability! Three malformations ).Ginger is “ generally recognized as safe ” by the Food by rancidity. Culinary herb, Food, and volatile Oils nausea and vomiting, and essential oil Flavor. 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